EMERGENCY OVERVIEW Water-white liquid with aromatic odor. Respiratory irritant. Skin and eye irritant. Flammable liquid. May polymerize and autoaccelerate if exposed to heat or mixed with catalyst, peroxide, metal halide, acids, or oxidizing agents resulting in rapid temperature rise and increased volatilization. Vapors are extremely flammable and are heavier than air.

POTENTIAL HEALTH EFFECTS:

EYE: Moderate eye irritant.

SKIN: May cause moderate skin irritation. A single, prolonged exposure is not likely to result in the material being absorbed through the skin in harmful amounts.

INGESTION: May be harmful if swallowed. Aspiration into the lung may cause fatal chemical pneumonitis. Excessive exposure may cause central nervous system depression (dizziness, drowsiness), nausea and loss of consciousness.

INHALATION: Short term exposure may cause respiratory irritation. Excessive exposure may cause central nervous system depression (dizziness, drowsiness), nausea and loss of consciousness. High concentrations may cause fatal cardiac arrhythmias

CHRONIC (CANCER) INFORMATION: Styrene is listed as a Group 2B substance (possibly carcinogenic to humans) by IARC.

TERATOLOGY (BIRTH DEFECT) INFORMATION: No evidence of teratological effects, based on animal studies or studies of exposed worker populations.

REPRODUCTION INFORMATION: No evidence of reproductive effects, based on animal studies or studies of exposed worker populations.

POTENTIAL ENVIRONMENTAL EFFECTS: Toxic to fish, invertebrates and microorganisms. No indication of cumulative toxicity. Compounds volatility would significantly limit persistence and mitigate the potential to produce adverse environmental impacts.

EYES: Flush eyes thoroughly with water for 15 minutes. Consult physician if irritation persists.

SKIN: Remove contaminated clothing and shoes. Wash affected area with soap and water. Do not reuse contaminated clothing without laundering. Consult physician if irritation persists.

INGESTION: Do not induce vomiting; consult physician immediately.

INHALATION: Remove victim to fresh air. Get medical assistance immediately. May cause chemical pneumonia if aspirated. Administer oxygen if there is difficulty breathing. Administer artificial respiration if not breathing.

NOTE TO PHYSICIANS

Do not induce vomiting. Because rapid absorption may occur through the lungs if aspirated, the decision of whether to induce vomiting should be made by a physician. If lavage is performed, suggest endotracheal and/or esophageal control. Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach. Remove contaminated clothing and wash affected areas with soap and water. Treat burns as thermal burns. Treatment based upon judgement of the physician in response to the reactions of the patient.

Flammable. Hot vapors are heavier than air and very flammable. Vapors may travel considerable distances to ignition source and cause flash fires or explosions.

HAZARDOUS COMBUSTION PRODUCTS: Carbon dioxide, carbon monoxide, and other toxic fumes of incomplete combustion. During a fire, smoke may contain mists of the original material.

EXTINGUISHING MEDIA: Carbon dioxide, foam or dry chemical. Water fog or fine spray; water may be ineffective. General purpose synthetic foams or protein foams are preferred.

FIRE FIGHTING INSTRUCTIONS: Releases flammable vapors below normal ambient temperatures. Use water spray to cool fire exposed containers, protect personnel, and disperse vapors and spills. Dike and collect water due to potential environmental damage and spread of fire with product carried across water surface. Use self-contained breathing apparatus and fight fire from safe distance due to explosion potential.

UNUSUAL HAZARDS ASSOCIATED WITH FIRE: Closed containers of Process Styrene may build up explosive pressures when exposed to the heat of fires. Closed containers of Process Styrene exposed to the heat of fires may begin to polymerize in an exothermic manner leading to autoacceleration and rapid pressure increase and explosion potential.

SMALL SPILL: Absorb spill with an inert material (dry sand) and place in chemical waste container for disposal (see section 13). Do not use reactive absorbents.

LARGE SPILL(on land): Remove all sparking devices and ignition sources. Contain spilled liquid with dikes of earth. Pump water into diked area and collect product from the top of water. Dispose of hydrocarbon laden water accordingly. Use oil spill collection pads and booms to contain runoff and seepage from diked areas.

SPILLS INTO WATERWAYS: Contain spill with oil booms and recover product by vacuum truck or oil collection pads.

REPORTABLE QUANTITY: 1000 pounds (Styrene)

HANDLING: May autopolymerize if uninhibited, heated or exposed to reactive contaminant with evolution of heat and flammable vapors.

Avoid contact with eyes. Avoid prolonged or repeated contact with skin. Keep containers tightly closed and use in well ventilated areas. Avoid prolonged or repeated breathing of vapors. Use grounding and bonding connections when transferring material to prevent static discharge, fire or explosion. Use spark proof tools and explosion proof equipment. Even empty containers may contain vapors. Do not cut, drill, grind or weld on containers, even if emptied of product.

STORAGE: Store in a cool area or refrigerated tank away from high temperatures, hot pipes or direct sunlight. Maintain Process Styrene temperature in storage below 90°F (32°C). Maintain inhibitor concentration above 10 ppm. If storage of more than 6 weeks is required aerate once per week with dry air to maintain dissolved oxygen above 10 ppm.

ENGINEERING CONTROLS: Use local ventilation to maintain airborne concentrations below exposure limits. Use only with adequate ventilation.

RESPIRATORY PROTECTION: For operations where inhalation exposure may occur, a NIOSH approved air purifying respirator with organic vapor cartridge(s) or canister may be permissible. Protection provided by air purifying respirators is limited. Use a positive-pressure air-supplied respirator if there is any potential for uncontrolled release or any other circumstances where air-purifying respirators may not provide adequate protection.

SKIN PROTECTION: When contact may occur, use protective clothing and gloves impervious to hydrocarbon materials. Use of specific items such as face shield, apron, gloves, boots or body suit is dependent upon operation. Wash hands thoroughly before eating, drinking or smoking.

EYE PROTECTION: Use safety glasses when handling small amounts. When splashing may occur use chemical splash goggles and face shield. If vapors cause eye discomfort use a full-face, supplied-air respirator.

CHEMICAL STABILITY: Stable under recommended storage conditions. Inhibited with tertiary-butyl-catechol (TBC). Maintain temperature below 90°F (32°C). Maintain oxygen content above 10 ppm.

CONDITIONS TO AVOID: Avoid excessive heat and keep away from open flames or ignition sources. Avoid dead-headed pumps while transferring.

INCOMPATABILITY: Do not use copper or brass tubing or connections. Do not mix with oxidizing agents, acids, metal halides or peroxides.

HAZARDOUS DECOMPOSITON PRODUCTS : Emits acrid fumes on decomposition

HAZARDOUS POLYMERIZATION: Polymerization may occur if exposed to excessive heat or catalyzed by mixture with incompatible materials. Polymerization is exothermic and may result in autoacceleration and increased pressure, venting of container, and a fire or explosion hazard.

This product has not been tested. Styrene exposure produces moderate acute toxicity in animals. Xylene exposure may cause CNS depression and damage to hearing. Unless specifically noted, the effects listed below are related to styrene monomer.

EYE EFFECTS: Moderate eye irritant. Eye irritation effects are reversible.

SKIN EFFECTS: Moderate skin irritant. Skin absorption exposure does not produce signs or symptoms of health hazards. Excessive or repeated contact can may cause dermatitis. Not expected to be a sensitizer

ACUTE ORAL EFFECTS:	Styrene	LD50 rat 2650 mg/kg.	LD50 mouse 316 mg/kg.
	Xylenes	LD50 rat 4300 mg/kg.
	Cumene	LD50 rat 1400 mg/kg.	LD50 mouse 12750 mg/kg.

ACUTE INHALATION EFFECTS:	Styrene	LC50 rat 12 gm/m3/4H	LC50 mouse 9500 mg/m3/4H
	Xylenes	LC50 rat 5000 ppm/4H
	Cumene	LC50 mouse 10 gm/m3/7H

SUBCHRONIC EFFECTS: Repeat dose toxicity studies show the mouse is sensitive to styrene induced toxicity with hyperplasia and fibrosis in lung tissue and atrophy and degeneration of nasal olfactory after chronic exposure. Some investigations indicate mild permanent hearing loss in rats exposed to repeated high styrene doses but no neurological or behavioral changes. Workers exposed to styrene may show minor impairment of color discrimination.

CHRONIC EFFECTS / CARCINOGENICITY: Rodent bioassays using rats and mice show no evidence of carcinogenicity in rats. Data for the mouse indicate an increase in late-onset tumors in the lung only. Studies demonstrate that the mouse lung converts styrene to a locally toxic metabolite while damage in negligible in the rat lung and not detected in the human lung. Listed by IARC as possibly carcinogenic to humans (Group 2B) based on limited evidence in humans and animal studies.

TERATOLOGY: Animal studies indicate styrene is not a teratogen. Available human data provides no evidence of an effect of styrene on the unborn child.

REPRODUCTION: Reproductive studies of rats exposed with inhalation and drinking water have shown no evidence of toxicity to testis or ovary or adverse affects on fertility. Studies in male workers exposed to styrene do not indicate any adverse effect to reproductive function

MUTAGENICITY: Tests in rats, mice and hamsters generally show no increase in chromosomal aberrations although some weakly positive effects were shown. In vitro tests are generally negative but occasional positive results have been reported that may reflect conversion of styrene to styrene oxide. Investigations of exposed worker populations have not shown conclusive evidence of genotoxicity in humans.

ECOTOXICITY: The EC50 for Pimephales promelas (fathead minnow) for 96 hour styrene exposure was 4-10 mg/L. The EC50 for Selenastrum capricornutum (algae) for 72 hour styrene exposure was 4.9 mg/L. The EC50 for Daphnia magna (aquatic invertebrate) for 48 hour styrene exposure was 4.7 mg/L.

CHEMICAL FATE INFORMATION: Biodegradation - styrene is readily biodegradable in aerobic conditions. Styrene readily volatilizes to the atmosphere. Half life in water is estimated at 4 hours. Bioaccumulation - Not expected to bioaccumulate.

DISPOSAL: USEPA RCRA hazardous waste if discarded (RCRA hazardous waste code D001). Recycle or incinerate at a USEPA approved facility or dispose in compliance with Federal, State, and local regulations.

RECYCLING OPPORTUNITIES: Downgraded or unused product could possibly be returned to Deltech for recycling if certain criteria are met. Contact a Deltech sales representative for more information.

Not meant to be all inclusive.

US FEDERAL / STATE REGULATIONS: (STYRENE CAS No. 100-42-5)

TSCA: This product is listed on the TSCA inventory.

OSHA: Hazardous by definition of Hazard Communication Standard (29CFR 1910.1200)

CERCLA: SARA TITLE III SECTIONS 311 AND 312 HAZARD CATEGORY:
  Acute Health Hazard
  Chronic Health Hazard
  Fire Hazard
  Reactive

  This notice must not be detached from the MSDS and fulfills the requirements for supplier notification.

CERCLA: SARA TITLE III SECTION 313: This product is a TRI reportable chemical.

CLEAN AIR ACT AMENDMENTS: TITLE III: This product is a listed hazardous air pollutant.

VOLATILE ORGANIC COMPOUNDS (VOC's): This product is considered a VOC and is expected to be photochemically active.

LISTED ON ONE OR MORE STATE HAZARDOUS SUBSTANCES LIST:
  CALIFORNIA
  FLORIDA
  MASSACHUSETTS
  MINNESOTA
  NEW JERSEY
  PENNSYLVANIA

INTERNATIONAL REGULATIONS:

AUSTRALIA (AICS): Listed

CANADA (DSL): Listed

EUROPEAN UNION (EINCS): Listed 202-851-5

CHINA (IECS): Listed

JAPAN (ENCS): Listed

KOREA (ECL): Listed

PHILIPPINES (PICCS): Listed

MSDS STATUS:

All sections revised to bring MSDS in compliance with the ANSI Z400.1-1998 Standard (Revised 8/03).

NATIONAL FIRE PROTECTION ASSOCIATION (NFPA) SYSTEM RATING:

The NFPA system rating for this product is:  Fire - 3    Health - 2    Reactivity - 2

This material may be regulated by Louisiana's Right-To-Know Law, R.S.30:2361 ET SEQ.